Start from Madame Tussauds and drive west on the A501 towards Paddington. Take the A40 and then the A413 towards Amersham.
Follow signs for Aylesbury and take the A4010. Enter Princes Risborough, a beautiful Buckinghamshire town, featured frequently in films and television programs.
Take the A4129 as far as Thame, another unique Buckinghamshire village, where you drive onto the A418.
Merge onto the A40 and drive towards Burford, a picturesque fifteenth century town. Then take the A417, signposted to Gloucester (pronounced Gloster), and merge back onto the A40.
Enjoy the South Wales countryside. Keep on the A40 towards Monmouth through Newport.
Drive through Newport on the B4237, following signs to Cardiff.
Enter Cardiff on the A48.