A hot day can turn quickly into a chilly evening in Tel Aviv-Yafo and dressing in layers will help you maintain your body temperature regardless of the weather. Pack both short-sleeved and long-sleeved shirts, along with at least one sweater and a fleece jacket. In addition, bring both shorts and long pants and wear one under the other when your day includes both beach and city activities. A single pair of flip-flops and a good pair of black, comfortable shoes should cover footwear. If you are traveling in winter, bring a rain slicker to protect you from frequent downpours.
If you are female and plan to visit holy sites such as synagogues while in Tel Aviv-Yafo, you should pack calf-length skirts and shirts that have sleeves below elbow length. Males should avoid wearing shorts to synagogues, though jeans are acceptable. For women visiting mosques, a head covering is also required. Mosques forbid wearing shoes inside their doors, so both men and women should wear flip-flops that are easy to slip off and leave outside.
Although Tel Aviv-Yafo is a modern city, you will pay extremely high prices if you must refill a prescription while on vacation. Bring enough medication to last your entire trip. In addition, bring a typewritten pharmacist scrip with you that includes the generic name of the medication you are carrying. This will help you through Israeli customs and will help you refill your prescription if you lose your supply while traveling abroad.