Call the major car rental companies. Ask them for their lowest rates. Mention corporate rates and other discounts that they may apply to your account. Compare any specials they are offering to the discounted rates.
Check to see what else the company offers such as unlimited miles or additional charges after so many miles. Factor these provisions into the prices.
Advise the car rental company that you may have flexible dates if this is possible. Many companies offer weekend or weekday special rates or extra off for booking on certain days of the week. If you have flexibility, use these promotions to your advantage.
Investigate what other offers the company has such as frequent-flier miles. If you use a rental car often, the miles can add up substantially over time.
Buy five, get one free. Some companies offer free days after so many paid trips. Look into this possibility, and take advantage of it if you can.
Choose the correct car size for your needs. Comfort is important, but if you can go with a compact or sub-compact vehicle you can save money as well. Compare the rates versus full-size car rates. Also, ask if they have free upgrades.