Purchase luggage that comes with stain-resistant cloth. A common option is vinyl luggage. Stains can be quickly wiped off with water and cleaner.
Place all liquids into plastic, Ziploc bags. More than one item can be placed in each bag, but make sure each bag is closed tightly. If a liquid spills, the bag should contain the mess.
Store nesting suitcases separately. Storing them together increases the risk of dirt from inside one getting on the exterior of another. Wrap each suitcase in a plastic bag if storing them together.
Apply a fabric protector on the exterior and interior of the luggage. Fabric protectors help to repel stains if something should get on the fabric. It is also effective in blocking stains.
