Get your group together. Find out how many of your friends are in for Spring Break in Myrtle Beach.
Prioritize what your group wants to do. If you're looking to spend the whole time on the beach, you'll need a beach front hotel. If you want to walk to the nightclubs, you'll want a place near the bars.
Look online for spring break deals. There are entire websites devoted to offering you these packages. Call hotels and ask about spring break deals, too.
Consider renting a condo or house if you have a lot of people going along. This will give you some privacy and keep you from getting into trouble with other hotel patrons.
Plan to share a room. Figure out if everyone needs their own bed or if you can double up. Splitting rooms will save you big money.
Book your transportation. Buy plane tickets and rent a car or figure out who's going to drive there. Consider changing your travel dates to weekdays to get a cheaper rate.
Pack your swimwear and think layers. Myrtle Beach tends to still be cooler around spring break time, so make sure you pack appropriate clothing.